What Is Dehydration:
Dehydration is an excessive loss of body fluids. It occurs when the output
of fluid exceeds fluid intake.
- Side effects of treatment such as vomiting or diarrhea can lead to chemotherapy
- Infections, high fever, bleeding, or even something as simple as not drinking enough
fluids can also lead to dehydration.
- The danger of dehydration is greatest for a person living alone, as he/she may not
recognize the signs and effects of dehydration.
- Chemotherapy Dehydration is a dangerous symptom, one that can be life threatening
if the signs are not recognized and treated. When a person suffers
from dehydrated, he may need to seek medical help to receive intravenous fluids.
A person can live for a long time without eating, but can function only a short
time without fluids.
- Electrolytes, such as potassium and sodium, are always present in the blood.
When these electrolytes are too high or too low, they can cause problems.
Some can be life-threatening. Confusion and disorientation are symptoms of
dehydration resulting from an electrolyte imbalance. Thus, a person who
is having severe vomiting or diarrhea should not be left alone to care for him or
herself. When a person suffers from dehydration, it is difficult to judge how well
he/she is doing and whether or not he/she needs help because of this confusion.
- Dry mucous membranes (dry mouth)
- Your skin may appear loose and crinkled and could keep standing up in a tent when
lightly pinched and pulled up.
- Secretions may become thick and dry.
- Little or no urine output.
How to Manage the Effects of Dehydration:
- The best way to treat chemotherapy dehydration is to prevent it.
Recognize early symptoms of dehydration such as thirst and dry mouth and take steps
to rehydrate yourself.
- Try to estimate how much fluid is lost and how much is taken in. It is not
easy to tell how much fluid a person is losing unless it is being measured.
Keeping a count of how many times a person is having diarrhea or vomiting may be
easier than actually measuring the amount, and this information will be very helpful
when talking to the doctor about chemotherapy dehydration symptoms. It is
also important to keep track of how much fluid is taken in.
- Increase fluid intake. If fluids cannot be kept down, sometimes
taking small pieces of ice works better, but it takes a lot of ice to get enough
fluid. Taking small sips frequently is better tolerated than drinking large
amounts. Fluids such as water, soda, bouillon, juice, or whatever is tolerated
can be tried. Alcohol and caffeine should be avoided because they increase
the effects of dehydration.
- Minimize or eliminate fluid loss when signs of dehydration are present.
The first step is to stop the diarrhea or vomiting and to continue drinking fluids
to replace those lost. Stopping diarrhea or vomiting usually requires medication.
If pills are vomited, rectal suppositories are available. In some cases of
chemotherapy dehydration, an injection may be needed.
- If you are vomiting, stop eating. Once you stop vomiting, start back on food
slowly. Start with small amounts of clear liquids, such as broth, juice soda,
sports drinks, or water. Then, advance to light, mild foods like jello,
bananas, rice, or toast. Soon, you will be back to solid foods.
- Avoid caffeine and smoking when symptoms of dehydration are present.
- Suck on hard candy, popsicles, or ice if you are susceptible to chemotherapy dehydration.
- Take the medications for nausea and vomiting as prescribed by your doctor.
If you are running low, ask for a refill.
- Notify your nurse or doctor if you feel nauseated during chemotherapy.
- Drink plenty of clear fluids (8-10 glasses per day) to fight off the effects of
chemotherapy dehydration. Examples: Gatorade, broth, jello, water, etc.
- Eat small amounts of soft bland low fiber foods frequently. Examples: banana,
rice, noodles, white bread, skinned chicken, turkey or mild white fish.
- Avoid foods such as:
- Greasy, fatty, or fried foods.
- Raw vegetables or fruits.
- Strong spices.
- Whole grains breads and cereals, nuts, and popcorn.
- Gas forming foods & beverages (beans, cabbage, carbonated beverages).
- Lactose-containing products, supplements, or alcohol.
- Limit foods and beverages with caffeine and beverages extremely hot or cold.
Medication (available over-the-counter - please read label to make
sure you can take this medication):
- Loperamide (Imodium®)
- Kaopectate II®caplets
- Maalox Anti-Diarrheal Caplets®
- Pepto Diarrhea Control® (follow instructions on
- Avoid: herbal supplements (milk thistle, cayenne, ginseng, saw
palmetto, and others).
- Clean skin around anus gently with warm water and soft cloth then dry gently and
- May apply a barrier cream (such as Desitin®) to
- Allow the irritated skin to be exposed to open air as much as possible.
Medications That May Be Prescribed by Your Health Care Provider:
Vomiting: If the chemotherapy you are taking is
likely to cause or has caused nausea and vomiting, your doctor may prescribe one
or more of the following common anti-nausea medications:
- Dolasetron (Anzemet®)
- Granisetron (Kytril®)
- Ondansetron (Zofran®)
- Proclorperazine (Compazine®)
- Promethazine (Anergan®),Phenergan®)
- Lorazepam (Ativan®)
- Metoclopramide (Reglan®)
- Dexamethasone (Decadron®)
- Famotidine (Pepcid®)
- Ranitidine (Zantac®)
These can be prescribed for you to take before, during, and/or after chemotherapy.
As you can see, there are many different medications that your doctor can prescribe
to control these symptoms that could lead to chemotherapy dehydration. It
may take trying a couple different medications before finding the right match for
Diarrhea: Your health care provider may recommend
some of the available over-the-counter medications. If these medications are
unsuccessful against your symptoms of dehydration, there are possible prescriptions
that may be recommended:
- Diphenoxylate - atropine sulfate (Lomotil®)
- Tincture of Opium
- Depending on the degree if dehydration, your doctor may recommend intravenous (IV)
fluids. Sometimes this may be done as an outpatient. In severe cases,
hospitalization could be required.
When to Contact Your Doctor or Health Care Provider:
Nausea and vomiting:
Note: nausea and vomiting can also be caused by medical conditions
unrelated to chemotherapy. Therefore, it is important to call your doctor if:
- You continue to suffer from nausea and vomiting despite taking your anti-nausea
- Nausea that interferes with your ability to eat.
- Vomiting 4-5 times in a 24 hour period.
- Feel bloated.
- Have pain or a swollen stomach before nausea and vomiting occurs.
- If you are bothered by side effects from the anti-nausea medications.
- Temperature greater than 100.5 F (38 C).
- Moderate to severe abdominal cramping/pain/straining/bloating.
- Black or blood in stools.
- If dietary measures and medication do not decrease the diarrhea.
Signs of chemotherapy dehydration:
- Dark (concentrated) urine.
- Dry mouth and skin.
Your doctor should be notified immediately if you experience:
- Sudden rapid or irregular heart beat.
- Blue lips
- Rapid breathing
- Excessive sleepiness with difficulty arousing.
Note: We strongly encourage you to talk with your health care professional
about your specific medical condition and treatments. The information contained
in this website about chemotherapy dehydration and other medical conditions is
meant to be helpful and educational, but is not a substitute for medical advice.