Late Effects of Chemotherapy Treatments in Childhood, Adolescent, and Young Adult Cancer Survivors

Late Effects of Chemotherapy

Late effects is a term used to describe a broad range of persistent adverse effects related to the disease process, its therapy, or both.  The onset may be unpredictable (months or years after completion of therapy).

It is estimated that while most childhood cancer survivors enjoy good health, at least 40% have significant disabilities that affect their quality of life.

Factors Associated with the Development of Late Effects:

• location and extent of primary disease
• type and intensity of the initial treatment
• age and physiological and developmental status of child at the time of diagnosis and treatment
• genetic or familial predisposition that may interact with treatment-related  injuries

Categories of Late Effects:

• Physical: all systems of the body can be affected; secondary cancers
• Emotional:  psychological, social adjustments, and academic difficulties
• Economic:  financial and uninsurability concerns and employment issues

Note:  We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice.